It all depends on the project and stem count.
However, the one thing I always make certain to nail is naming tracks/parts. I used to do the whole colouring thing and it was fine with smaller stem count projects but with genres like pop I get huge stem counts and colouring doesn’t cut it. Grouping like for like in folders, saving specific routing templates etc are a must for me. It’s all about saving time and keeping things uncluttered.
I think, certainly for me, key commands are more important as they help navigate without the need for a gazillion clicks.
Everything else, I wing it.